Novel transcript, sense intronic to C4orf51 (C4orf51 intronic transcript)

This entry describes a novel, poorly characterized transcript within the C4orf51 gene locus. The provided Ensembl ID (ENSG00000295738) does not correspond to *C4orf51* or any well-documented protein-coding gene in major resources. *C4orf51* itself encodes a 202-amino-acid, predicted nuclear protein containing a DUF4722 domain. There are multiple transcript variants of *C4orf51*, but the function of both the canonical protein and the sense intronic transcripts is unknown; experimental evidence for a protein product from the sense intronic transcript is lacking. There are no associations with pharmacological modulation. Deletions covering *C4orf51* and neighboring genes have been implicated in multiple congenital anomalies, but the specific contribution of this gene or its intronic transcripts is unclear. There is no clear evidence that this transcript itself encodes a protein, nor that it functions as a pharmacologically targetable molecule. There is not enough information to designate it as a bona fide therapeutic target or to classify it within established molecular families. No evidence for interactions with known drugs, validated disease associations, or therapeutic modalities.

Other names

C4orf51Chromosome 4 open reading frame 51