Novel transcript antisense to alcohol dehydrogenase 4, alcohol dehydrogenase 6, and alcohol dehydrogenase 1A (LOC100507053 (also ENSG00000246090))

LOC100507053 (ENSG00000246090) is classified as a long non-coding RNA (lncRNA) that acts as a natural antisense transcript to the genes alcohol dehydrogenase 4 (ADH4), alcohol dehydrogenase 6 (ADH6), and alcohol dehydrogenase 1A (ADH1A). Its specific molecular function remains uncharacterized, but as an antisense transcript, it is hypothesized to function as a local regulator of gene expression, potentially modulating the expression of genes involved in processes such as secretion, metabolism, fibroblast activation, and the maintenance of tissue barriers[1][3][5]. There is no evidence to suggest it functions directly as a receptor, enzyme, or classical therapeutic target. Its role is currently understood to be in RNA-based regulation rather than as a protein-coding gene. It is not commonly referenced as a disease biomarker, pharmacological target, or safety concern.

Other names

ENSG00000246090LOC100507053novel transcript antisense to ADH4, ADH6 & ADH1A