Novel transcript antisense to biotinidase (ENSG00000294157)

ENSG00000294157 is an antisense transcript overlapping the sense strand of the biotinidase (BTD) gene. Antisense transcripts are a class of non-coding RNAs transcribed from the opposite DNA strand of a protein-coding gene; they can modulate the expression of their corresponding sense gene by mechanisms such as chromatin remodeling, transcriptional interference, RNA masking, and double-stranded RNA-mediated pathways. The biological role of any specific antisense transcript is often undiscovered and context dependent; there is currently no evidence that "novel transcript, antisense to BTD" serves as a therapeutic target, biomarker, or has a direct role in disease. Such transcripts may contribute to gene regulatory networks, possibly affecting the expression or stability of the biotinidase gene product, but there are no established clinical or pharmacological applications for this transcript.

Other names

antisense to BTD