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ENSG00000226999 is annotated as a “novel ubiquitin-like ribosomal protein pseudogene.” Pseudogenes are nonfunctional DNA segments that closely resemble functional genes but do not produce functional protein products due to disabling mutations or loss of regulatory elements[2][4][5]. This particular pseudogene is expressed at the RNA level in some tissues (such as primordial germ cells in the gonad), but there is no evidence it encodes a functional protein or has a biological role[3][5]. As with other pseudogenes, it may retain high sequence similarity to ancestral protein-coding genes and could theoretically participate in gene regulation via noncoding RNA transcripts, but no such function is reported for this locus[4][5][6]. Because it is not a functioning gene or protein, it is not considered a receptor, enzyme, transporter, or other classical therapeutic target[2][4][5].
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