Target intelligence / Profile preview

Nuclear envelope integral membrane protein 2 (NEMP2)

Target
NEMP2
Molecular classification
Other (Integral membrane protein of the nuclear envelope)
01

Overview

Nuclear envelope integral membrane protein 2 (NEMP2) is a protein encoded by the NEMP2 gene and localizes to the inner membrane of the nuclear envelope[1][2][3][9]. It is a predicted transmembrane protein believed to be involved in maintaining nuclear envelope structure and organization[2][3]. NEMP2 has been associated with certain genetic diseases, such as Hemochromatosis type 4 and cone-rod dystrophy 1, but there is limited evidence of its direct role as a therapeutic target or established biomarker[2]. No drugs are currently known to interact with this protein in a clinical context.

Other names
TMEM194BTransmembrane protein 194BUPF0571 transmembrane proteinNEMP2
02

Biological functions

Nuclear envelope structurePossibly involved in nuclear membrane organizationPossibly acts upstream of or within oocyte maturation (non-human models)
03

Disease associations

Hemochromatosis (Type 4)Cone-rod dystrophy 1

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