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Nuclear Export
- Molecular classification
- Cellular Transport Process
01
Overview
Nuclear export is a fundamental cellular process by which molecules, such as proteins and RNA, are transported from the nucleus to the cytoplasm through nuclear pore complexes. This process is essential for proper cell function, as it regulates the localization of key molecules involved in gene expression, signal transduction, and cell cycle control.
02
Mechanism of action
Inhibition of CRM1-mediated nuclear export
03
Biological functions
Protein localizationRNA localizationGene regulationQuality controlmRNA transporttRNA transport
04
Disease associations
CancerDrug resistance
05
Interacting drugs
Leptomycin B
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