Nuclear factor, erythroid 2 like 3 pseudogene 1 (NFE2L3P1)

Nuclear factor, erythroid 2 like 3 pseudogene 1 (NFE2L3P1) is annotated as a *pseudogene* in the human genome, related by sequence similarity to the functional gene NFE2L3 (Nuclear factor, erythroid 2 like 3) but lacking evidence for protein expression or biological function. Pseudogenes are segments of DNA similar to known genes but generally non-functional due to mutations, deletions, or truncations that prevent their expression as proteins. Unlike NFE2L3, which is a transcription factor belonging to the CNC-bZIP family and involved in cancer and cellular homeostasis[2], NFE2L3P1 does not function as a receptor, enzyme, transcription factor, or any other therapeutic target class. There is no evidence that NFE2L3P1 interacts with drugs, acts as a biomarker, or is associated with disease biology. Its inclusion in target lists is likely due to nomenclature confusion or incomplete curation.\n\nNote:\nIf you intended to refer to *NFE2L3* (\"Nuclear factor, erythroid 2 like 3\"), this is a functional transcription factor involved in cell cycle, cancer, and stress responses[2], but *NFE2L3P1* is a pseudogene. This makes NFE2L3P1 *incorrect* as a therapeutic target or receptor.

Other names

NFE2L3P1

Null (No mechanism, not a target)