Target intelligence / Profile preview

Nuclear pore complex-interacting protein family member A2 (NPIPA2)

Target
NPIPA2
Molecular classification
Other (protein associated with the nuclear pore; not receptor, enzyme, transporter, ion channel, transcription factor, histone modifier, etc.)
01

Overview

Nuclear pore complex-interacting protein family member A2 (NPIPA2) is a human protein localized at the nuclear membrane and predicted to be part of the nuclear pore complex. It is thought to function in mRNA and protein transport across the nuclear envelope, facilitating nucleocytoplasmic transport. The protein is not well characterized in the literature, and its specific roles, disease involvement, and therapeutic relevance remain largely unexamined. There is no evidence it serves as a conventional therapeutic target or as a biomarker, and no drugs are associated with NPIPA2. The gene is referenced in several genomic databases, confirming its sequence and standard aliases, but no clear molecular family fit (such as receptor, enzyme, etc.) is provided. Disease associations in available sources are primarily computational or text-mined and do not establish causality or clinical relevance.

Other names
NPIPNPIPA1nuclear pore complex interacting protein family member A2Nuclear pore complex interacting protein family member A1
02

Biological functions

mRNA transportProtein transportPossible involvement in nucleocytoplasmic transport
03

Disease associations

None clearly established; there is text-mining association with "Herpes Zoster Oticus" and "Facial Neuralgia" (per GeneCards), but these appear to be weak associations and not confirmed causal roles

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