Target intelligence / Profile preview

Nuclear pore complex interacting protein family member B12 (NPIPB12)

Target
NPIPB12
Molecular classification
Other
01

Overview

Nuclear pore complex interacting protein family member B12 (NPIPB12) is a protein encoded in humans by the NPIPB12 gene located at chromosome 16p11.2. It is classified as a protein-coding gene, but there is very limited functional characterization or biological data available for this protein. There is no evidence it functions as a receptor, enzyme, transporter, or other classical therapeutic target class, nor is it described in association with disease, biomarker use, or drug interactions[2][4][6]. - *NPIPB12* is annotated as a protein-coding gene, but no detailed functional, disease association, or drug-targeting roles have been described in the available human protein/gene databases[2][4][6]. - It is not counted among the canonical components of the nuclear pore complex (NPC); those are typically the nucleoporins (Nups), with defined functions in nucleocytoplasmic transport[1][3][5]. - The limited records indicate this gene/protein is present in the genome but lacks both functional assignment and characterization in the therapeutic or biomarker context[2][4][6]. - Thus, this entry is **likely incorrect as a therapeutic target**—it does not meet criteria for a "receptor, enzyme, transporter," or similar functional entity, and no literature supports roles in disease or druggability.

Other names
NPIPB12nuclear pore complex-interacting protein family member B12

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