Target intelligence / Profile preview

Nuclear pore complex-interacting protein family member B13 (NPIPB13)

Target
NPIPB13
Molecular classification
Other, membrane protein, nuclear pore complex-interacting protein family
01

Overview

Nuclear pore complex-interacting protein family member B13 (NPIPB13) is a protein encoded by the NPIPB13 gene and classified as a member of the nuclear pore complex interacting protein family. The protein is predicted to be membrane-associated and has been annotated on the basis of sequence homology, but its exact cellular and molecular function remains uncharacterized in experimental literature[3][7]. There is no evidence that NPIPB13 participates directly in molecular transport, signaling, enzymatic activity, or other processes typical for therapeutic targets such as receptors, ion channels, or transporters. The gene has some genetic association with arthrogryposis multiplex congenita, but no causative or mechanistic data have been reported[3]. NPIPB13 is not listed as a therapeutic target and there are no known interacting drugs, biomarker roles, or safety concerns at this time. The most specific classification is a membrane protein of the nuclear pore complex-interacting protein family, but its biological and clinical relevance remains to be established.

Other names
NPIPB13nuclear pore complex interacting protein family member B13Putative NPIP-like protein LOC613037nuclear pore complex interacting protein member
02

Mechanism of action

None established

03

Biological functions

Unknownimplicated in nuclear pore complex interactioninferred functions may include nucleocytoplasmic transport due to family association
04

Disease associations

Arthrogryposis multiplex congenita (limited genetic association)

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