Nuclear pore membrane glycoprotein 210-like (NUP210L)

NUP210L (Nuclear pore membrane glycoprotein 210-like) is a protein-coding gene related to nuclear pore structure, primarily predicted to function in the development of Sertoli cells and spermatids and likely localizes to the nuclear periphery, especially in elongating spermatids[3][5][6][7]. It is implicated in male reproductive disorders such as spermatogenic failure and oligoasthenoteratozoospermia, but there is no evidence supporting a therapeutic target role, drug interactions, or utility as a biomarker in clinical settings[3][5][7]. Additional context and issues: - The query names a "novel transcript, sense intronic to NUP210L," abbreviated as "ENSG00000300617." There is no official Ensembl gene with this identifier. The valid Ensembl gene ID for NUP210L is ENSG00000143552[3][5][7]. "ENSG00000300617" does not correspond to any recognized gene and likely reflects a fictitious or misannotated entry. - No evidence supports that any "novel transcript, sense intronic to NUP210L" is a characterized therapeutic target, receptor, transporter, or enzyme. - There is no indication that such a transcript has a canonical full name, abbreviation, recognized function, or relevance in pharmacology. Summary of key decisions: - "is_incorrect" is set to true due to the use of an invalid or unrecognized gene ID and the absence of a therapeutically relevant target. - No interacting drugs, mechanisms of action, biomarkers, or safety concerns are known. - NUP210L is best classified as "Other" in molecular classification, reflecting its role in nuclear pore function but not as a target class (receptor/enzyme, etc.). - No aliases specific to the queried "novel transcript" exist; those listed belong to NUP210L. - All available function and disease links are tied to role in spermatogenesis and not to therapeutics.

Other names

Nucleoporin 210 likeNUP210L