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Nuclear Protein

Molecular classification: Histone, Transcription factor, Splicing factor, GTPase, Other

Overview

A nuclear protein is any protein that is located within the cell nucleus. These proteins play essential roles in various nuclear processes, including DNA replication, transcription, RNA processing, and chromatin organization. Examples include histones, transcription factors, splicing factors, and Ran GTPase. They are involved in gene expression, RNA processing, DNA repair, and the formation of regulatory complexes. Nuclear proteins can be further localized within sub-nuclear compartments such as the nucleolus, splicing speckles, PML/ND10 bodies, and the nuclear periphery.

Biological functions

Chromatin organizationGene regulationRNA processingDNA repairCell cycleTranscriptionmRNA maturationHomologous recombinationmiRNA processing

Disease associations

CancerOther

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