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Nuclear transcription factor Y subunit alpha pseudogene 1 (NFYAP1) is a human pseudogene (NCBI Gene: 100130677). It is classified as a non-functional copy of the NFYA gene, which encodes a subunit of the NF-Y trimeric transcription factor complex responsible for binding CCAAT motifs within promoter regions and regulating gene expression. Pseudogenes like NFYAP1 typically do not encode functional proteins and are not directly implicated in disease, therapeutic targeting, or molecular function. Key points for clarity: NFYAP1 is a pseudogene and should not be confused with the functional NFYA gene, which forms part of a trimeric transcription factor involved in gene regulation. There is no evidence NFYAP1 acts as a therapeutic target, molecular biomarker, or has studied disease associations; functional relevance lies in NFYA. The entry is marked as "is_incorrect: true," as the reference for a therapeutic target is invalid when the entity is a pseudogene.
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