Drug pipeline
Full profile accessExplore the programs pursuing this target and their development progress.
- Drug candidates
- Developers
- Development stage
Target intelligence / Profile preview
Nuclear transport factor 2 like export factor 2 (NXT2)
- Target
- NXT2
- Molecular classification
- Other, Nuclear transport factor, mRNA export factor
01
Overview
Nuclear transport factor 2 like export factor 2 (NXT2) is a protein containing an NTF2 domain, involved in the trafficking of macromolecules and RNA between the cytoplasm and nucleus[2][3][6][8]. NXT2 forms heterodimers with other nuclear export factors and plays a key role in mRNA export pathways, potentially by regulating the movement of NES-containing proteins, and is highly expressed in testis, implying a specialized function in spermatogenesis[1][4][8]. Diseases associated with NXT2 include male infertility, but it is not considered a direct therapeutic drug target at this time[3].
- Other names
- NTF2-related export protein 2NXT2BM-025DC9P15-2Protein p15-2
02
Biological functions
Trafficking of macromolecules, ions, and small molecules between cytoplasm and nucleusmRNA nuclear exportRegulator of protein export for NES-containing proteinsPotential role in spermatogenesis (testis-enriched expression)
03
Disease associations
Male infertility(weakly) Cancer
Beyond the preview
Go deeper on Nuclear transport factor 2 like export factor 2 (NXT2).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Clinical trials
Full profile accessFollow the clinical studies evaluating therapies directed at this target.
- Trial design
- Status
- Readouts
Competitive landscape
Full profile accessCompare approaches across drug candidates, modalities, and indications.
- Programs
- Modalities
- Indications
Literature & evidence
Full profile accessInvestigate the research and source evidence behind target biology and development.
- Publications
- Sources
- Analysis
Patents
Full profile accessExplore patent activity around therapies and technologies addressing this target.
- Patents
- Assignees
- Technologies
Research & analysis
Full profile accessConnect target biology, drug development, and emerging evidence in your research.
- Biology
- Development news
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Nuclear transport factor 2 like export factor 2 (NXT2).