Nucleophosmin 1 pseudogene 1 (NPM1P1)

Nucleophosmin 1 pseudogene 1 (NPM1P1) is a non-functional pseudogene related to the NPM1 gene, which encodes nucleophosmin, a nucleolar phosphoprotein involved in various cellular processes, including ribosome biogenesis and regulation of the cell cycle. As a pseudogene, NPM1P1 does not code for an active protein product and is not considered a therapeutic target, receptor, or enzyme. Its sequence is similar to the functional NPM1 gene, but it generally lacks the capacity for protein translation due to mutations, truncations, or regulatory loss. There is no evidence for a direct functional, pathogenic, or therapeutic role for NPM1P1, nor is it involved in drug interactions or known as a biomarker. Any referenced roles in disease or therapy involving nucleophosmin are specific to the parent gene NPM1, and not its pseudogene. NPM1 itself is a well-characterized protein involved in important biological functions and is implicated in various cancers, but NPM1P1 does not share these roles. Many pseudogenes, including NPM1P1, may have regulatory roles at the RNA level (sometimes as competing endogenous RNAs in rare cases), but there are no well-established or widely studied functions for NPM1P1 in this respect. If you are seeking therapeutic targets in the nucleophosmin family, refer instead to NPM1 (nucleophosmin 1), not its pseudogenes. Nucleophosmin 1 pseudogene 1 (NPM1P1) is not a protein-coding gene nor a therapeutic target. It is a pseudogene, and any references as a direct biological or pharmacological target are incorrect.

Other names

NG1-1.6NPMP1