Nucleophosmin 1 pseudogene 17 (NPM1P17)

Nucleophosmin 1 pseudogene 17 (NPM1P17) is a processed pseudogene in the human genome, related to the functional gene NPM1, which encodes a multifunctional nucleolar protein implicated in ribosome biogenesis, cell cycle regulation, genomic stability, and is an important oncogenic driver in acute myeloid leukemia[1][3][5][7]. Pseudogenes such as NPM1P17 do not generally encode functional proteins but can sometimes be transcribed as noncoding RNAs. In some instances, pseudogenes exert regulatory effects through RNA-mediated interaction networks, particularly if expressed; however, regulatory activity for NPM1P17 specifically has not been reported in the scientific literature[2][4][6][8]. NPM1P17 is not considered a molecular target for therapeutic intervention, does not have documented disease associations, drug interactions, or established biomarker utility. Summary of critical points: - NPM1P17 is a **pseudogene** of nucleophosmin 1. - Pseudogenes are DNA sequences resembling known genes but typically lack protein-coding ability and canonical target functions[4][8]. - NPM1P17 is **not recognized** as a drug target, biomarker, or molecular classifier in disease or therapeutic contexts. - Function (if any) would be as a *regulatory noncoding RNA*, but direct evidence in NPM1P17 is not available.

Other names

NPM1P17nucleophosmin 1 (nucleolar phosphoprotein B23, numatrin) pseudogene 17