Nucleophosmin 1 pseudogene 19 (NPM1P19)

Nucleophosmin 1 pseudogene 19 (NPM1P19) is a non-coding pseudogene related to the NPM1 gene, which encodes nucleophosmin, a multifunctional chaperone protein involved in ribosome biogenesis, cell proliferation, and cancer biology[1][3]. Pseudogenes like NPM1P19 share sequence similarity with their parent genes but lack coding potential due to mutations or deletions and are typically biologically inactive. Unlike NPM1, which plays well-established roles in cancer—particularly acute myeloid leukemia—NPM1P19 has no known biological function, disease association, or role as a drug target. Key clarifications: - NPM1P19 is not a receptor, enzyme, transporter, channel, or signaling protein. It is a pseudogene, which generally do not produce functional proteins or serve as drug targets. - Information about NPM1 (not NPM1P19) includes critical roles in cancer prognosis, transcriptional regulation, and its use as a biomarker in acute myeloid leukemia[1][3]. However, these properties do not apply to pseudogenes such as NPM1P19. Summary for later structured extraction: NPM1P19 is a pseudogene with no established therapeutic, biological, or disease-related role, and is not a real molecular target for drugs or biomarker development. Any references connecting it with disease or function are likely erroneous or due to mistaking it for its parent gene, NPM1.

Other names

NPM1P19

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