Nucleophosmin 1 pseudogene 26 (NPM1P26)

Nucleophosmin 1 pseudogene 26 (NPM1P26) is a pseudogene—that is, a genomic DNA sequence similar to the NPM1 gene but typically non-functional and does not produce a functional protein product. Pseudogenes usually result from gene duplication or retrotransposition but lose coding capacity due to mutations. There is currently no evidence that NPM1P26 serves as a therapeutic target, is involved in human disease, or interacts with any drugs. Standard biological classification does not include NPM1P26 as a member of functionally-defined gene families such as receptors, enzymes, or transcription factors. There are no known utility, biomarker roles, or safety concerns associated with NPM1P26. This entry is not considered a canonical therapeutic target, and there does not appear to be significant published information or biomedical relevance associated with NPM1P26. If you are searching for the related protein-coding gene, you may be interested in “Nucleophosmin 1 (NPM1),” a nucleolar phosphoprotein with roles in ribosome biogenesis and cancer biology, which is entirely distinct from this pseudogene.