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Nucleophosmin 1 pseudogene 45 (NPM1P45) is a non-protein-coding genomic sequence with high similarity to the functional NPM1 gene. Pseudogenes are considered inactive remnants of once-functional genes, usually resulting from gene duplication or retrotransposition. NPM1P45 does not produce a functional protein and has no direct known role in physiology or disease. Unlike the canonical NPM1 gene, which is essential in ribosome biogenesis, genomic stability, and cancer development[5][7], NPM1P45 is not implicated in biological processes, disease, or targeted by any drugs.
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