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Nucleophosmin 1 pseudogene 46 (NPM1P46) is annotated as a pseudogene related to the nucleophosmin 1 (NPM1) gene. Pseudogenes are non-functional segments of DNA similar to known genes but do not encode functional proteins. NPM1P46 is therefore not a protein, receptor, or enzyme and has no known biological function, disease association, or drug interaction. In contrast, the canonical NPM1 gene is a multifunctional nucleolar protein essential for ribosome biogenesis, genome stability, cell cycle regulation, and is implicated in multiple cancer pathologies[1][3][5][7]. There is no evidence that NPM1P46 acts as a disease biomarker or therapeutic target.
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