Nucleophosmin 1 pseudogene 47 (NPM1P47)

Nucleophosmin 1 pseudogene 47 (NPM1P47) is a genomic sequence resembling the functional NPM1 gene, but considered a pseudogene—meaning it does not code for a functional protein and has no established biological, pharmacological, or pathological role. NPM1 pseudogenes may exist due to duplication or retrotransposition events and chiefly serve as evolutionary remnants. While the parent gene *NPM1* encodes a nucleolar phosphoprotein implicated in cancer and cell proliferation[1][2], pseudogenes like NPM1P47 are not targets for pharmacological intervention and are usually ignored in drug development and translational biology. If the intention was to inquire about the canonical functional NPM1 gene (not the pseudogene NPM1P47), then NPM1 is a well-established therapeutic target in oncology; however, NPM1P47 itself is not an actionable target[1][2].

Other names

NPM1P47Nucleophosmin 1 pseudogene 47

Not applicable; pseudogenes like NPM1P47 have no described mechanisms for drug action.