Nucleophosmin 1 pseudogene 52 (NPM1P52)

Nucleophosmin 1 pseudogene 52 (NPM1P52) is a processed pseudogene related to the NPM1 gene, which encodes the nucleophosmin protein—a critical cellular chaperone and regulator of ribosome biogenesis, genomic stability, cell cycle, and apoptosis[1][3][5][7][8]. Unlike its functional parent gene, NPM1P52 does not express a protein product. However, some pseudogenes, including those of NPM1 family genes, may be transcribed and participate in regulatory networks through non-coding RNA functions, such as acting as microRNA decoys or contributing to the RNA interference pathway[2][4]. While pseudogenes can modulate disease-relevant biological processes, they are not typically direct therapeutic targets, and no drugs or biomarkers are assigned to NPM1P52 itself. There’s no evidence in current biomedical literature of NPM1P52 functioning as a classical receptor, enzyme, transporter, transcription factor, or a direct disease marker. If structured data is needed, these values adhere to the commonly accepted conventions in molecular target annotation. The entry is "incorrect" as a therapeutic target, as it does not correspond to a protein-coding receptor or enzyme or any established drug target class.

Other names

nucleophosmin (nucleolar phosphoprotein B23, numatrin) pseudogenenucleophosmin 1 (nucleolar phosphoprotein B23, numatrin) pseudogene 52NPM1P52