Nucleoporin 50 pseudogene 1 (NUP50P1)

Nucleoporin 50 pseudogene 1 (NUP50P1) is a non-coding pseudogene related to the nucleoporin 50 (NUP50) gene. NUP50P1 is not known to encode a functional protein, nor does it serve as a therapeutic target, biomarker, or drug interaction partner. Pseudogenes like NUP50P1 typically arise from duplication or retrotransposition events and retain sequence similarity to their parent functional gene but contain disruptive mutations and are not expressed or do not produce a functional protein. In this case, the functional gene NUP50 codes for an FG-repeat nucleoporin that participates in nuclear transport and nuclear pore complex assembly, but NUP50P1 itself has no such roles[1][5]. Clarification: - The actual therapeutically relevant protein is "Nucleoporin 50 (NUP50)", not NUP50P1. References found in scientific literature and databases discuss NUP50 and its roles, but there are no entries describing NUP50P1 as a functional gene or protein[1][5]. - Multiple pseudogenes of NUP50 are annotated on chromosomes 5, 6, and 14, but these do not code for functional proteins[1]. Summary of correctness: There is something wrong with this target as provided: NUP50P1 is a pseudogene, not a protein-coding gene or drug target[1][5]. If the intention is to refer to the functional protein, the correct target should be "Nucleoporin 50 (NUP50)".

Other names

NUP50P1NUP50P-1