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Nucleosome assembly protein 1 like 6, pseudogene (NAP1L6P)

Target: NAP1L6P
Molecular classification: Other (Pseudogene)

Overview

Nucleosome assembly protein 1 like 6, pseudogene (NAP1L6P) is a non-protein-coding pseudogene in the human genome, related to the NAP1 family which are histone chaperones involved in nucleosome assembly and chromatin dynamics[2][1]. Unlike the functional NAP1 family members, NAP1L6P does not encode a protein, but its transcript may exert regulatory effects, such as acting as a competing endogenous RNA or miRNA decoy, thereby influencing the expression of related genes[5]. Some studies have assigned functional regulatory roles to long non-coding RNAs transcribed from pseudogenes, including associations with cancer biology via post-transcriptional regulation mechanisms[3][6]. However, NAP1L6P is not a direct target for current therapeutic drugs or interventions, and its biological significance remains incompletely determined.

Other names: NAP1L6PNAP1L6FLJ33596lncNAP1L6Putative nucleosome assembly protein 1-like 6

Biological functions

Potential regulation of gene expression via non-coding RNA mechanisms (e.g., as competing endogenous RNA [ceRNA] or miRNA sponge)[3][5]Predicted involvement in nucleosome assembly through sequence similarity to protein-coding relatives[2]

Disease associations

Has been reported in the context of cancer biology (e.g., prostate cancer progression, likely via RNA regulatory mechanisms)[6]

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