NudC domain-containing protein 2 (NUDCD2)

NudC domain-containing protein 2 (NUDCD2) is a cytoplasmic protein that participates in protein folding and enables unfolded protein binding. It may regulate the LIS1/dynein pathway by stabilizing LIS1 with Hsp90 chaperone, impacting cell migration and preventing centriole amplification. It is implicated in neural development through potential association with lissencephaly. There is no evidence that NUDCD2 is a conventional therapeutic target (e.g., receptor, enzyme, transporter) nor that it interacts directly with any drugs, serves as a clinical biomarker, or presents known safety concerns. The name is correctly spelled and specific; all common aliases are listed. Its molecular class is best described as “Other,” reflecting its role in protein interaction and cellular regulation, primarily in protein folding and microtubule-associated processes.

Other names

NudCL2DKFZp686E10109RGD1307203RIKEN cDNA 2700047N05nudC domain-containing protein 2NudC-like protein 2NUDC2