NUS1 pseudogene 3 (NUS1P3)

NUS1 pseudogene 3 (NUS1P3), also known as YDD19, is classified as a pseudogene unrelated to the protein-coding NUS1 gene. Unlike NUS1—which encodes the Nogo-B receptor (NgBR), a critical subunit in cis-prenyltransferase complexes essential for protein glycosylation, dolichol biosynthesis, and has a clear role in human disease—NUS1P3 has no known coding potential or biological activity[4][5][6]. There are no reports linking NUS1P3 to human disease, drug interaction, or biomarker applications. No molecular function or action has been attributed to NUS1P3 in curated scientific databases. Key clarification: - NUS1 pseudogene 3 (NUS1P3) is distinct from the protein-coding NUS1 gene and should not be mistaken for a functional protein, therapeutic target, or disease gene. NUS1, not NUS1P3, encodes the Nogo-B receptor involved in congenital disorders of glycosylation, neurological diseases, and targets of medical interest[1][3][5][7]. NUS1P3 itself is inactive and is included in gene catalogs due to genetic sequence similarity with NUS1, but it does not code for protein or confer biological function.

Other names

YDD19