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Target intelligence / Profile preview
NUT family member 2D (NUTM2D)
- Target
- NUTM2D
- Molecular classification
- Other (protein-coding gene, no clear assignment to typical receptor, enzyme, ion channel, transporter, or transcription factor categories)
01
Overview
NUT family member 2D (NUTM2D) is a protein-coding gene in humans, located on chromosome 10, also known by aliases such as FAM22D[7][3]. It is part of the NUTM2 gene family, which includes paralogs NUTM2A and NUTM2B[7]. The precise biological function of NUTM2D is not well characterized in the literature; it is annotated as a protein-coding gene with no current evidence implicating it as a classic therapeutic target, receptor, or enzyme. Mutations or expression changes in related NUTM family members have been observed in several disease contexts, but NUTM2D itself is currently only weakly linked to disease (e.g., noted association with retinitis pigmentosa in genetic databases, but direct functional or pathogenic involvement is not established)[7][6]. NUTM2D has not been described as a drug target, biomarker, nor associated with pharmacological mechanism or safety concerns. Its molecular classification is best categorized as "Other," pending further research into its molecular and cellular roles[7][6][3].
- Other names
- FAM22DNUTM2DNUT family member 2Dfamily with sequence similarity 22, member Dprotein FAM22D
02
Mechanism of action
None established (no drugs known to act via NUTM2D)
03
Biological functions
Unknown/Other (no clearly established biological functions; possibly associated with mRNA processing/assembly based on related family studies, but direct evidence for NUTM2D lacking)
04
Disease associations
Other (associated with Retinitis Pigmentosa, evidence of possible involvement in cancer through paralogs/family associations, but no established or direct disease causality)
05
Safety considerations
None established (no therapeutic targeting or associated drug safety literature)
06
Interacting drugs
None known
07
Biomarkers
None established (NUTM2D not described as a biomarker for therapy or diagnosis)
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