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NUT family member 2E (NUTM2E)

Target: NUTM2E
Molecular classification: Other (non-enzymatic, non-receptor protein)

Overview

NUT family member 2E is a protein encoded by the NUTM2E gene in humans. While its precise biological role remains unclear, NUTM2E has been identified as a protein-coding gene, and alterations involving this gene are implicated in certain rare cancers, including kidney clear cell sarcoma and kidney sarcoma. Its gene is also noted as sharing paralogy with NUTM2B. NUTM2E is not classified as an enzyme, receptor, or transporter and does not have recognized involvement in pathways typically targeted by current therapeutics. Presently, there are no drugs, biomarkers, or safety concerns directly linked to NUTM2E.

Other names: NUTM2EFAM22Efamily with sequence similarity 22 member ENUT family member 2E

Biological functions

Unknown; specific biological functions are not well-characterized in current databases

Disease associations

Cancer (notably, associated with kidney clear cell sarcoma and kidney sarcoma)

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