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Nutrient depletion refers to the reduction or loss of essential nutrients—such as nitrogen, phosphorus, and potassium—from an environment like soil or water. This process can occur due to natural factors (e.g., erosion) or human activities such as intensive agriculture and pollution. In soils, nutrient depletion leads to decreased fertility and productivity; in aquatic systems, it disrupts ecological balance and can harm organisms like fish by reducing the availability of vital elements needed for life[2][3][7]. The phenomenon is not a molecular target but rather an environmental condition or process that impacts biological systems at the ecosystem level.
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