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Nutritional absorption enhancement" refers to strategies, agents, or interventions aimed at increasing the efficiency by which dietary nutrients (e.g., carbohydrates, proteins, fats, minerals, and vitamins) are absorbed from the gastrointestinal tract into the body. These may include pharmacological, nutritional, biotechnological, or formulation approaches that modulate the function or expression of membrane transporters (such as SGLT1, PepT1), alter intestinal permeability (including tight junction modulators), increase the emulsification or solubilization of nutrients, or positively influence the gut microbiota. It is a biological process or therapeutic strategy, not a discrete molecular target or receptor.
Enhancement of membrane permeability; Modulation of tight junctions; Use of absorption enhancers such as surfactants, chelators, or enzyme inhibitors; Increasing transport protein activity or expression (e.g., SGLT1 for glucose, PepT1 for peptides); Alteration of gut microbiome to increase breakdown and solubility of nutrients
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