Target intelligence / Profile preview

Obturator nerve

Molecular classification
Other (peripheral nerve, not a molecular or receptor family)
01

Overview

The obturator nerve is formed by nerve roots from L2-L4 of the lumbar plexus and passes through the pelvis to innervate muscles in the medial thigh compartment. It supplies motor function to muscles responsible for thigh adduction and sensory function to the medial skin of the thigh, and also sends articular branches to the hip and knee joints. Clinically, it may be targeted during surgical nerve block procedures to reduce sensation and pain in knee and pelvic surgeries. Damage or injury to the obturator nerve can result in pain, loss of thigh adduction, and mobility issues.

Other names
Nervus obturatoriusn. obturatorius
02

Mechanism of action

Functional inactivation via local anesthetic nerve block for pain control during surgery

03

Biological functions

Motor innervation to medial thigh muscles (hip adductors: adductor longus, adductor brevis, gracilis, obturator externus, adductor part of adductor magnus, sometimes pectineus)Sensory innervation to skin of medial thighArticular (joint) innervation to hip and knee
04

Disease associations

Other (Obturator nerve injury/neuropathy, not classical disease roles such as cancer or inflammation)
05

Safety considerations

Risk of injury during pelvic/hip/knee surgery (neuropathy, pain, motor deficit)Complications from obturator nerve block (risk of incomplete anesthesia, nerve damage)
06

Interacting drugs

Local anesthetics (used in obturator nerve block)

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