Target intelligence / Profile preview

Octanoate

Molecular classification
Fatty acid anion, Straight-chain saturated fatty acid anion, Conjugate base of octanoic acid
01

Overview

Octanoate is a straight-chain saturated fatty acid anion that is the conjugate base of octanoic acid (also known as caprylic acid). It has a molecular formula of C8H15O2- and a molecular weight of approximately 143.20 g/mol. Octanoate is believed to block adipogenesis and has roles as both a human metabolite and a Saccharomyces cerevisiae metabolite. It is commonly found in the form of sodium octanoate (sodium caprylate) or other salts such as lithium octanoate. Octanoate is significant in biochemical studies, particularly in examining lipid-protein interactions within cellular membranes. It has applications in colloidal chemistry for investigating the formation and stability of micelles and bilayers in various aqueous environments. Additionally, it is used as a protein stabilizer for molecules such as albumin and fibrinogen and has potential antimicrobial properties. Octanoate is also involved in studies focusing on enhancing the solubility and bioavailability of poorly soluble chemicals, providing insights into chemical formulation and delivery systems.

Other names
CaprylateCapryloaten-octanoateCaprilateOctanoic acid anionCaprylic acid anion
02

Mechanism of action

Stabilizes proteins such as albumin and fibrinogen. Has surfactant properties useful in stabilizing emulsions and foams. May have antimicrobial activity.

03

Biological functions

Human metaboliteSaccharomyces cerevisiae metaboliteMay block adipogenesisInvolved in lipid metabolism
04

Disease associations

May have relevance in metabolic illnesses such as non-alcoholic fatty liver disease (NAFLD)Potential role in insulin resistance
05

Safety considerations

Can cause skin irritationCan cause serious eye irritation

Beyond the preview

Go deeper on Octanoate.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Drug pipeline

Full profile access

Explore the programs pursuing this target and their development progress.

  • Drug candidates
  • Developers
  • Development stage

Clinical trials

Full profile access

Follow the clinical studies evaluating therapies directed at this target.

  • Trial design
  • Status
  • Readouts

Competitive landscape

Full profile access

Compare approaches across drug candidates, modalities, and indications.

  • Programs
  • Modalities
  • Indications

Literature & evidence

Full profile access

Investigate the research and source evidence behind target biology and development.

  • Publications
  • Sources
  • Analysis

Patents

Full profile access

Explore patent activity around therapies and technologies addressing this target.

  • Patents
  • Assignees
  • Technologies

Research & analysis

Full profile access

Connect target biology, drug development, and emerging evidence in your research.

  • Biology
  • Development news
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on Octanoate.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call