Target intelligence / Profile preview

Octocrylene

Molecular classification
Other (organic small molecule; UV filter; not a receptor, enzyme, transporter, etc.)
01

Overview

Octocrylene is a clear, oil-soluble, organic compound (C24H27NO2) widely used in sunscreens and cosmetics for its capacity to absorb UVB and short UVA rays. Its strong photostability makes it an essential photoprotective agent, helping prevent the degradation of both formulations and other UV-sensitive ingredients. Octocrylene acts as a UV filter, conferring broad-spectrum sun protection, and is valued for its compatibility with oils and other cosmetic ingredients. Its use reduces the risk of sunburn, premature skin aging, and skin cancer. However, some safety concerns exist regarding skin sensitivity, photoallergic reactions, and potential environmental impacts.

Other names
2-Ethylhexyl 2-cyano-3,3-diphenylacrylate2-Propenoic acid, 2-cyano-3,3-diphenyl-, 2-ethylhexyl esterOctocrilene
02

Mechanism of action

physical absorption and dissipation of UV radiation

03

Biological functions

Absorption of UVB and short UVA radiationPhotostabilizer (stabilizes other UV-sensitive ingredients)
04

Disease associations

Other (prevents sunburn and UV-induced skin damage; reduces risk of skin cancer with regular use in sunscreens)
05

Safety considerations

Potential for allergic reactions or skin sensitivity, especially in individuals with photoallergyPossible generation of free radicals under UV exposure if not properly formulatedEnvironmental concerns, including coral bleaching under certain conditions

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