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Target intelligence / Profile preview
Ocular Surface Tear Film (Tear Film)
- Target
- Tear Film
- Molecular classification
- Fluid, Secretory Product, Extracellular Matrix Component
01
Overview
The tear film is a thin, multi-layered fluid coating that covers the ocular surface, including the cornea and conjunctiva. It is composed of lipid, aqueous, and mucin components, each contributing to lubrication, protection, and optical clarity. Tear film dysfunction is a major contributor to dry eye disease.
- Other names
- Tear FilmPrecorneal FilmLacrimal Fluid
02
Mechanism of action
N/A
03
Biological functions
LubricationOptical ClarityBarrier FunctionNutrient DeliveryWound HealingAntimicrobial Defense
04
Disease associations
Dry Eye DiseaseKeratoconjunctivitis SiccaMeibomian Gland DysfunctionCorneal UlcerLid Wiper Epitheliopathy
05
Safety considerations
Hypersensitivity to components of artificial tearsBacterial contamination of artificial tearsSteroid-induced glaucoma or cataractsAntibiotic resistance
06
Interacting drugs
Artificial Tears
4 more in the full profile.
07
Biomarkers
Tear OsmolarityMatrix Metalloproteinase-9 (MMP-9)LactoferrinLysozymeTear Film Break-Up Time (TBUT)Schirmer's Test
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