OFD1 pseudogene 17 (OFD1P17)

OFD1 pseudogene 17 (OFD1P17) is a member of the OFD1 pseudogene family. Pseudogenes are DNA sequences similar to genes but typically nonfunctional; they do not produce active proteins and have lost their protein-coding potential. OFD1P17 is named for its similarity to the OFD1 gene, which is responsible for encoding a protein involved in cilia formation and human development. While the canonical OFD1 gene is linked to disorders such as oral-facial-digital syndrome type I, OFD1 pseudogenes like OFD1P17 do not have established biological activity, disease relevance, or therapeutic targeting roles[7].\n\nKey clarifications:\n- There is a risk of confusion with the canonical OFD1 gene, which is a disease-associated protein-coding gene implicated in developmental syndromes[1][3][7][8].\n- OFD1P17 is explicitly classified as a pseudogene, meaning it is not expected to be a receptor, enzyme, transporter, or any other druggable molecular target[7].\n- There are no known drugs, mechanisms of action, biomarker roles, or safety concerns associated specifically with OFD1P17[7].\n- Aliases listed overlap with other OFD1 family members or pseudogenes—appropriate caution should be taken in data mapping.\n\nThis entry should not be considered a valid molecular target for therapeutic intervention or biomarker use.

Other names

71-7A371-7A5C5orf1OFD1P1OFD1 pseudogene 1oral-facial-digital syndrome 1 pseudogeneoral-facial-digital syndrome 1pseudogene 1OFD1P17