OFD1 pseudogene 7 Y-linked (OFD1P7Y)

OFD1P7Y is a pseudogene on the Y chromosome, derived from the OFD1 gene family through retroposition and duplication events during mammalian sex chromosome evolution[1]. Unlike the functional OFD1 gene on the X chromosome, which encodes a centrosomal and ciliary protein implicated in disorders such as oral-facial-digital syndrome type 1 and related ciliopathies[2][4][5], OFD1P7Y does not encode a functional protein and lacks evidence of therapeutic or pathological roles[3][6]. Pseudogenes are typically non-coding DNA sequences resembling known genes but lacking regulatory or coding potential, and are not considered drug targets, receptors, enzymes, or clinically relevant biomarkers. The various Y-linked OFD1 pseudogenes, including OFD1P7Y, are identified by sequence homology but are not expressed or functional in humans. No diseases, drugs, or known biological processes are directly attributed to OFD1P7Y. Therefore, this entry is considered incorrect for lists of therapeutic targets or receptors, and should not be used for drug discovery or disease association purposes[1][3][6].

Other names

OFD1P7OFD1PY7OFDYP7OFD1 pseudogene, Y-linked 7oral-facial-digital syndrome 1 pseudogeneOFD1P7Y