Target intelligence / Profile preview

Olfactory receptor 10G3 (OR10G3)

Target
OR10G3
Molecular classification
G protein-coupled receptor, Receptor, 7-transmembrane receptor
01

Overview

Olfactory receptor 10G3 is a member of the G protein-coupled receptor (GPCR) superfamily specifically expressed in the olfactory epithelium, where it binds odorant molecules and initiates a G protein-mediated signal transduction cascade that ultimately results in the perception of smell[1][2][3][4]. Like other olfactory receptors, it possesses a characteristic 7-transmembrane domain structure and is transcribed from a single coding exon[1][4]. The OR10G3 gene is not a pseudogene and is one of the many functional human olfactory receptor genes[2][3]. Despite evidence that some olfactory receptors have physiological roles outside of olfaction, there is currently no established link between OR10G3 and specific diseases or drug responses[9].

Other names
Olfactory receptor family 10 subfamily G member 3OR14-40HsOR14.2.2ORL3695AE000658-DOlfactory receptor OR14-40
02

Biological functions

Signal transductionRecognition of odorant moleculesSensory perception of smell
03

Disease associations

Other (no direct established role in classic disease categories; some evidence for broader physiological roles for olfactory receptors, but no data for OR10G3 specifically)[9]

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