Target intelligence / Profile preview

Olfactory receptor 11H6 (OR11H6)

Target
OR11H6
Molecular classification
G protein-coupled receptor, Olfactory receptor, Receptor, Transmembrane protein
01

Overview

Olfactory receptor 11H6 is a member of the olfactory receptor family in humans, encoded by the OR11H6 gene. Like other olfactory receptors, it is a G protein-coupled receptor (GPCR) characterized by a 7-transmembrane domain structure common to many neurotransmitter and hormone receptors. It is responsible for recognizing specific odorant molecules in the nasal epithelium and initiating a signal transduction cascade via G proteins, which leads to the perception of smell. The olfactory receptor gene family is the largest in the human genome, and individual receptors typically display selective responses to different odorant ligands such as isovaleric acid[1][5][8][9].

Other names
Olfactory receptor, family 11, subfamily H, member 6OR11H6
02

Mechanism of action

G protein-mediated transduction of odorant signals

03

Biological functions

Signal transductionOlfactory signal detectionSensory perception
04

Disease associations

Other
05

Interacting drugs

Isovaleric acid

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