Olfactory receptor 13C5 (OR13C5)

Olfactory receptor 13C5 (OR13C5) is a human protein encoded by the *OR13C5* gene, and is part of the extensive olfactory receptor gene family. These receptors are integral membrane proteins that belong to the G protein-coupled receptor (GPCR) superfamily, characterized by their seven transmembrane domains. In the human olfactory system, olfactory receptors, including OR13C5, interact with odorant molecules in the nose. This interaction initiates neuronal signaling via G protein-coupled mechanisms, ultimately resulting in the perception of smell. Each receptor is thought to be activated by a set of odorant molecules, though the precise ligand specificity of OR13C5 is not clearly established in the literature. The gene itself arises from a single coding exon, as is common for members of this family. Olfactory receptors are generally not considered tractable therapeutic targets due to their specialized function in olfaction and lack of evidence for involvement in major diseases outside of sensory perception.

Other names

OR13C5Olfactory receptor family 13 subfamily C member 5Olfactory receptor OR9-11OR9-11

None established for clinical drugs; in the nose, binds odorants and induces G protein-mediated transduction, but not targeted by therapeutics