Target intelligence / Profile preview

Olfactory receptor 1D5 (OR1D5)

Target
OR1D5
Molecular classification
G protein-coupled receptor, Receptor, Transmembrane protein, Olfactory receptor
01

Overview

Olfactory receptor 1D5 (OR1D5) is a member of the large family of olfactory receptors, which are G protein-coupled receptors (GPCRs) found primarily in the olfactory epithelium of the nose. These receptors are responsible for detecting odorant molecules and initiating the neuronal signals that result in the perception of smell. Like other olfactory receptors, OR1D5 possesses a seven-transmembrane domain structure and is encoded by a single coding-exon gene. This gene is located on human chromosome 17. Olfactory receptors are the largest gene family in the human genome and function primarily in olfactory signal transduction via G protein-mediated pathways. There are no well-documented associations of OR1D5 with major diseases, no approved drugs targeting this receptor, and it is not currently used as a biomarker or therapeutic target outside of basic research[1][3][10][12].

Other names
Olfactory receptor family 1 subfamily D member 5Olfactory receptor 1D5OR17-31Olfactory receptor 17-31C17orf2OR17-2OR17-30OR1D4Olfactory receptor OR17-2
02

Mechanism of action

Not applicable (no known drugs targeting this receptor)

03

Biological functions

Signal transductionSensory perception (specifically smell/olfaction)G protein-coupled receptor signaling
04

Disease associations

Other (no major disease association; a possible minor association with breast hypertrophy is mentioned, but this is not established as a well-validated disease mechanism)
05

Safety considerations

None known—no established safety issues as a direct therapeutic target
06

Interacting drugs

None known (no drugs are clinically or experimentally established to target OR1D5 directly)
07

Biomarkers

None known

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