Target intelligence / Profile preview

Olfactory receptor 1I1 (OR1I1)

Target
OR1I1
Molecular classification
G protein-coupled receptor (GPCR), 7-transmembrane receptor, Receptor
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Overview

Olfactory receptor 1I1 (OR1I1) is a member of the large family of olfactory receptors, which are responsible for the detection and discrimination of volatile odorant molecules in the environment. The protein is characterized by a 7-transmembrane domain structure typical of G protein-coupled receptors, facilitating odorant recognition and signal transduction via G-protein activation. Olfactory receptor gene families are among the largest in the human genome, arising from single coding-exon genes. In humans, these receptors are predominantly expressed in the olfactory epithelium and initiate neuronal responses that trigger the perception of smell. OR1I1 is not known to be targeted by any drugs and is not implicated as a biomarker or direct disease driver. Its primary role is in the physiological process of olfaction, and it is not considered a therapeutic target.

Other names
OR1I1OR19-20OR1I1POR1I1QOlfactory receptor family 1 subfamily I member 1Olfactory receptor 1I1Olfactory receptor 19-20
02

Mechanism of action

Signal transduction via activation by odorants, leading to G protein-mediated cascades in olfactory sensory neurons

03

Biological functions

Recognition of odorant moleculesG protein-mediated transduction of odorant signalsSignal transduction
04

Disease associations

Other (olfactory receptors are generally not directly implicated as disease drivers; rarely associated with disease phenotypes; limited evidence for involvement in any major disease class)
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Safety considerations

None reported; not a therapeutic target
06

Interacting drugs

None known. Olfactory receptors generally respond to odorant molecules, not approved drugs
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Biomarkers

None known or validated for clinical use

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