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Olfactory receptor 1I1 (OR1I1) is a member of the large family of olfactory receptors, which are responsible for the detection and discrimination of volatile odorant molecules in the environment. The protein is characterized by a 7-transmembrane domain structure typical of G protein-coupled receptors, facilitating odorant recognition and signal transduction via G-protein activation. Olfactory receptor gene families are among the largest in the human genome, arising from single coding-exon genes. In humans, these receptors are predominantly expressed in the olfactory epithelium and initiate neuronal responses that trigger the perception of smell. OR1I1 is not known to be targeted by any drugs and is not implicated as a biomarker or direct disease driver. Its primary role is in the physiological process of olfaction, and it is not considered a therapeutic target.
Signal transduction via activation by odorants, leading to G protein-mediated cascades in olfactory sensory neurons
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