Olfactory receptor 1L3 (OR1L3)

Olfactory receptor 1L3 (OR1L3) is a member of the large family of olfactory receptors, which are G protein-coupled receptors responsible for the initial detection of odorants in the nasal olfactory epithelium[5][7]. Like other olfactory receptors, OR1L3 features the characteristic seven-transmembrane domain structure of class A GPCRs and is primarily expressed in sensory neurons of the nose, where it mediates the detection of specific chemical odorants to initiate the sense of smell[4][7]. OR1L3 may also be expressed at low levels in non-olfactory tissues, but its physiological role is best established in olfactory signal transduction. To date, no drugs are known to specifically interact with OR1L3, nor is it associated with major diseases or utilized as a biomarker.

Other names

Olfactory receptor OR9-28Olfactory receptor 9-DOR9-28OR9-Dolfactory receptor, family 1, subfamily L, member 3

Not applicable (No drugs target OR1L3 directly; odorant molecules bind and activate via classic GPCR mechanisms)