Target intelligence / Profile preview

Olfactory receptor 56A4 (OR56A4)

Target
OR56A4
Molecular classification
G protein-coupled receptor (GPCR)[2][3][5], Receptor[2][5]
01

Overview

Olfactory receptor 56A4 (OR56A4) is a member of the olfactory receptor family, a large group of G protein-coupled receptors (GPCRs) responsible for detecting odorant molecules in the nasal epithelium, leading to perception of smell[2][5]. These receptors have a characteristic seven-transmembrane domain structure and function through G protein-mediated signal transduction, with binding of specific ligands (such as decanal and undecanal) triggering neuronal responses[2][3][5]. The OR56A4 gene is protein-coding and is not a pseudogene[4]. While primarily associated with olfactory function, there is limited data linking this gene to disease (e.g., Gait Apraxia)[5].

Other names
Olfactory receptor OR11-49OR11-49HsOR11.3.93[2][4][5]
02

Mechanism of action

Agonism by odorant molecules (ligands bind to the receptor, activate G protein-mediated transduction, leading to neuronal signaling)[2][3][5]

03

Biological functions

Odorant detection[2][3][5]Signal transduction (G protein-mediated)[2][5]
04

Disease associations

Other (associated with Gait Apraxia, limited evidence)[5]
05

Interacting drugs

Decanal[2]

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