Olfactory receptor 6B1 (OR6B1)

Olfactory receptor 6B1 (OR6B1) is a member of the olfactory receptor family, a large group of G protein-coupled receptors (GPCRs) responsible for the detection of odorant molecules in the nose, initiating neuronal responses that produce the perception of smell[1][3][7][5][9]. OR6B1 has a characteristic 7-transmembrane domain structure like other GPCRs and is encoded by a single coding-exon gene[3][6][12]. Olfactory receptors are the largest gene family in the human genome and typically mediate their effects via G protein-dependent signal transduction[3][4][7][5]. Although mainly implicated in olfaction, some olfactory receptors are known to have additional physiological roles in extra-nasal tissues, but no such nonolfactory role is currently established for OR6B1[7]. There are no known therapeutic drugs or direct disease involvements for OR6B1 as of now. **Notes:** - All names and identifiers (OR7-3, OR7-9, etc.) refer to the same protein, but "Olfactory receptor 6B1" and "OR6B1" are canonical[1][3][5][9]. - No evidence suggests this is an incorrect target or is misnamed. - No specific drugs, mechanism of action for drugs, biomarkers, or safety issues are documented for OR6B1 to date. - The "is_target" label is marked true because it is a receptor (a classical type of pharmacological target), though it is not an established therapeutic target.

Other names

OR7-3OR7-9olfactory receptor family 6 subfamily B member 1olfactory receptor 7-3olfactory receptor OR7-9

mechanisms of drugs for this specific OR, if any, are not established; general mechanism is G protein-mediated signal transduction upon odorant binding