Target intelligence / Profile preview

Olfactory receptor 7A10 (OR7A10)

Target
OR7A10
Molecular classification
G protein-coupled receptor, Receptor, 7-transmembrane receptor, Odorant receptor, Class A (Rhodopsin-like) GPCR, Olfactory receptor
01

Overview

Olfactory receptor 7A10 (OR7A10) is a member of the large olfactory receptor family in humans. These proteins are G protein-coupled receptors (GPCRs) with a characteristic 7-transmembrane domain structure. Olfactory receptors, including OR7A10, are primarily responsible for detecting odorant molecules in the nasal epithelium, initiating a neuronal response resulting in the perception of smell. OR7A10 is encoded by a single-exon gene and belongs to the Class A (Rhodopsin-like) GPCR superfamily, the largest gene family in the human genome. Although the primary role for OR7A10 is sensory transduction in the olfactory system, some olfactory receptors have been implicated in physiological functions outside the nose, though no therapeutic uses or drug targets are reported for OR7A10 specifically. There are no documented drugs, clinical biomarkers, or major disease associations directly involving this receptor [1][2][3][6][12][13].

Other names
OR19-18OST027BC85395_3CIT-HSP-146e8HsOR19Olfactory receptor OR19-18
02

Mechanism of action

Not applicable (no known therapeutically targeted mechanism; physiological mechanism is G protein-coupled transduction of odorant signals) [1][3][5]

03

Biological functions

Signal transductionOlfaction (smell perception)G protein-mediated signal transduction
04

Disease associations

Other (no direct disease association, but variants have been mentioned in the context of rare disorders such as Usher Syndrome type IIC and Charcot-Marie-Tooth disease type 4B2, generally incidental)

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