Olfactory receptor family 1 subfamily F member 12 pseudogene (OR1F12P)

The target "Olfactory receptor family 1 subfamily F member 12, pseudogene" (OR1F12P) is not a functional protein-coding gene but a pseudogene in humans, annotated as related to the family of olfactory receptors, which themselves are G protein-coupled receptors (GPCRs) that detect odorants. Functional olfactory receptors typically mediate signal transduction in sensory neurons and contribute to olfaction; however, as a pseudogene, OR1F12P is not translated into a functional protein and therefore does not perform olfactory or any other signaling functions. Pseudogenes may result from duplication or mutation of ancestral genes and do not have established physiological roles or relevance as therapeutic targets. There is no evidence of involvement in disease or interaction with drugs, nor is it considered a biomarker or subject to documented safety concerns. Note: This entry is "incorrect" as a therapeutic target; it is a pseudogene and not a functional receptor. For functional olfactory receptors, see the broader olfactory receptor family, which are true G protein-coupled receptors involved in sensory perception, but this specific gene (OR1F12P) does not encode such a receptor[1][4].

Other names

Olfactory receptor 1F12POR1F12hs6M1-35POR1F12QHs6M1-35POR6-12olfactory receptor 1F12olfactory receptor OR6-12olfactory receptor family 1 subfamily F member 12seven transmembrane helix receptor