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Olfactory receptor family 1 subfamily H member 1 pseudogene (OR1H1P) is a non-functional homolog of olfactory receptor genes. Olfactory receptors are typically G protein-coupled receptors that detect odorant molecules and initiate the sense of smell, but pseudogenes in this large family—estimated to be around 600 in humans[5]—are generally not transcribed or translated into functional proteins. OR1H1P does not code for an active olfactory receptor and has no documented physiological, pathological, or pharmacological significance. The gene is included in databases for completeness but is not considered a valid drug target, receptor, or biomarker[5]. Note: - If you are looking for active olfactory receptors, select genes designated without a "P" (for pseudogene) suffix and confirm protein coding status. - OR1H1P is not a suitable therapeutic or research target in molecular pharmacology or receptor biology. - Some databases may list "associations" with other genes or proteins based on sequence only, not functional evidence[6]. Most olfactory receptor pseudogenes, including OR1H1P, do not contribute to odorant detection or other G protein-coupled receptor-mediated functions in humans[5].
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