Target intelligence / Profile preview

Olfactory receptor family 1 subfamily M member 1 (OR1M1)

Target
OR1M1
Molecular classification
G protein-coupled receptor (GPCR), Receptor, Odorant receptor
01

Overview

Olfactory receptor family 1 subfamily M member 1 encodes an odorant GPCR expressed in the nasal olfactory epithelium, where it interacts with airborne odorant molecules to initiate neuronal responses resulting in the perception of smell[2][6]. Like other GPCRs, it consists of a seven-transmembrane domain and transduces signals via G proteins. The olfactory receptor gene family is the largest in the genome and features single coding-exon genes. While primarily involved in olfaction, emerging evidence suggests olfactory receptors may also be expressed in other tissues and could play nonolfactory physiological roles[1]. No established therapeutic or diagnostic uses for OR1M1 exist, and it is not a routine drug target[2][3][6].

Other names
OR1M1Olfactory receptor 1M1OR19-6Olfactory receptor 19-6Olfactory receptor OR19-5OR19-5
02

Mechanism of action

Ligand (odorant) binding resulting in G protein-mediated signal transduction

03

Biological functions

Signal transductionOdor perceptionG protein-mediated olfactory signaling
04

Disease associations

Other (No direct association with major diseases; possible involvement as indicated in pathway databases and some genetic associations such as discrete subaortic stenosis/subvalvular aortic stenosis)
05

Safety considerations

None reported related to therapeutic targeting, as olfactory receptors are not standard therapeutic targets
06

Interacting drugs

None routinely documented (Olfactory receptors generally do not have therapeutic drugs; their interaction is primarily with small molecule odorants)
07

Biomarkers

None established for patient selection or efficacy monitoring

Beyond the preview

Go deeper on Olfactory receptor family 1 subfamily M member 1 (OR1M1).

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Drug pipeline

Full profile access

Explore the programs pursuing this target and their development progress.

  • Drug candidates
  • Developers
  • Development stage

Clinical trials

Full profile access

Follow the clinical studies evaluating therapies directed at this target.

  • Trial design
  • Status
  • Readouts

Competitive landscape

Full profile access

Compare approaches across drug candidates, modalities, and indications.

  • Programs
  • Modalities
  • Indications

Literature & evidence

Full profile access

Investigate the research and source evidence behind target biology and development.

  • Publications
  • Sources
  • Analysis

Patents

Full profile access

Explore patent activity around therapies and technologies addressing this target.

  • Patents
  • Assignees
  • Technologies

Research & analysis

Full profile access

Connect target biology, drug development, and emerging evidence in your research.

  • Biology
  • Development news
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on Olfactory receptor family 1 subfamily M member 1 (OR1M1).

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call