Olfactory receptor family 1 subfamily N member 1 (OR1N1)

Olfactory receptor family 1 subfamily N member 1 (OR1N1) is a member of the large family of human olfactory receptors, which are integral membrane proteins belonging to the G protein-coupled receptor (GPCR) superfamily. These receptors contain a characteristic structure of seven transmembrane alpha helices and are expressed in the olfactory epithelium, where they interact with small, volatile odorant molecules to initiate olfactory signal transduction via G protein-mediated pathways[1]. Each olfactory receptor is capable of binding a subset of odorants, contributing to the combinatorial encoding of smells. There is little direct evidence that OR1N1 is involved in human disease or that it serves as a drug target. The nomenclature for olfactory receptors is complex and several synonyms listed here may refer to distinct receptor genes, so referencing with care is required.

Other names

Olfactory receptor 1N1OR1N1OR1N3 (potential mislabel, usually a separate gene)OR1-26 (possible database notation)Olfactory receptor 1-26 (not standard)Olfactory receptor 1N3 (potential error)Olfactory receptor OR9-22 (potential error)olfactory receptor, family 1, subfamily N, member 3 (possible confusion with OR1N3)

Activation by small volatile odorant molecules, leading to G protein signaling cascade[1].