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Olfactory receptor family 1 subfamily P member 1 (OR1P1)

Target
OR1P1
Molecular classification
G protein-coupled receptor (GPCR), Receptor (putative, if functional), Pseudogene (in almost all references)
01

Overview

Olfactory receptor family 1 subfamily P member 1 (OR1P1) is classified as a **pseudogene** in the human genome, with the official gene symbol OR1P1P in major databases. Olfactory receptors are a subset of G protein-coupled receptors (GPCRs) involved in detecting odorants in the nose and triggering signaling pathways that result in the perception of smell. Most olfactory receptor genes in humans are pseudogenes, and OR1P1 is characterized as "a segregating pseudogene, where some individuals have an allele that encodes a functional olfactory receptor, while other individuals have an allele encoding a protein that is predicted to be non-functional"[4]. It belongs to the largest gene family in the human genome. There are no established therapeutic or diagnostic applications for OR1P1 due to its pseudogene status. Some homologs in other species are functional, but in humans, OR1P1 is unlikely to have a functional protein product in most individuals. No drugs, safety concerns, or clinical implications have been reported for this gene[4][2]. Key points: - OR1P1 is best described as a non-functional or partially functional pseudogene for an olfactory receptor in humans, not a drug target[4][2]. - The gene has several alternative names, but all refer to the same entity. - It does not figure in therapeutic research or clinical practice.

Other names
OR1P1POR17-208Olfactory receptor 1P1Olfactory receptor OR17-9Olfactory receptor 17-208Olfactory receptor, family 1, subfamily P, member 1 pseudogene
02

Biological functions

Odorant recognition (in theory, where functional)G protein-mediated signal transduction (if expressed as functional protein)

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